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1

Clay nanoparticles for regenerative medicine and biomaterial design: a review of clay bioactivity

Mousa, Mohamed, Evans, Nicholas D., Oreffo, Richard O.C., Dawson, Jonathan I.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

2

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate

Dalby, Matthew J., Gadegaard, Nikolaj, Oreffo, Richard O. C.

Journal:

Nature Materials

Year:

2014

Language:

english

File:

PDF, 3.19 MB

english, 2014

3

The effect of measles vaccination in rhesus monkeys (Macaca mulatta)

MacArthur, J. A., Mann, P. G., Oreffo, V., Scott, G. B. D.

Journal:

Laboratory Animals

Year:

1982

Language:

english

File:

PDF, 744 KB

english, 1982

4

Trapping single human osteoblast-like cells from a heterogeneous population using a dielectrophoretic microfluidic device

Thomas, Rupert S. W., Mitchell, Peter D., Oreffo, Richard O. C., Morgan, Hywel

Journal:

Biomicrofluidics

Year:

2010

Language:

english

File:

PDF, 906 KB

english, 2010

5

Gene therapy used for tissue engineering applications

Mieke Heyde, Kris A. Partridge, Richard O. C. Oreffo, Steven M. Howdle, Kevin M. Shakesheff, Martin C. Garnett

Journal:

Journal of Pharmacy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.52 MB

english, 2007

6

Tantalum trabecular metal – addition of human skeletal cells to enhance bone implant interface strength and clinical application

J. O. Smith, B. G. Sengers, A. Aarvold, E. R. Tayton, D. G. Dunlop, R. O. C. Oreffo

Journal:

Journal of Tissue Engineering and Regenerative Medicine

Year:

2012

Language:

english

File:

PDF, 505 KB

english, 2012

7

Nanotopography induced osteogenic differentiation of human stem cells

E.J. Kingham, M. Tsimbouri, N. Gadegaard, M.J. Dalby, R.O.C. Oreffo

Journal:

Year:

2011

Language:

english

File:

PDF, 123 KB

english, 2011

8

The potential of biomimesis in bone tissue engineering: lessons from the design and synthesis of invertebrate skeletons

D. Green, D. Walsh, S. Mann, R.O.C. Oreffo

Journal:

Year:

2002

Language:

english

File:

PDF, 253 KB

english, 2002

9

Hope versus hype: what can additive manufacturing realistically offer trauma and orthopedic surgery?

Gibbs, David MR, Vaezi, Mohammad, Yang, Shoufeng, Oreffo, Richard OC

Journal:

Regenerative Medicine

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

10

Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes

Alvarez, Karl, de Andrés, María C, Takahashi, Atsushi, Oreffo, Richard O C

Journal:

BMC Musculoskeletal Disorders

Year:

2014

Language:

english

File:

PDF, 501 KB

english, 2014

11

The chorioallantoic membrane (CAM) assay for the study of human bone regeneration: a refinement animal model for tissue engineering

Moreno-Jiménez, Inés, Hulsart-Billstrom, Gry, Lanham, Stuart A., Janeczek, Agnieszka A., Kontouli, Nasia, Kanczler, Janos M., Evans, Nicholas D., Oreffo, Richard OC

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.28 MB

english, 2016

12

Preservation and stability of cell therapy products: recommendations from an expert workshop

Stacey, Glyn N, Connon, Che J, Coopman, Karen, Dickson, Alan J, Fuller, Barry, Hunt, Charles J, Kemp, Paul, Kerby, Julie, Man, Jennifer, Matejtschuk, Paul, Moore, Harry, Morris, John, Oreffo, Richard

Journal:

Regenerative Medicine

Year:

2017

Language:

english

File:

PDF, 992 KB

english, 2017

13

Translation of remote control regenerative technologies for bone repair

Markides, Hareklea, McLaren, Jane S., Telling, Neil D., Alom, Noura, Al-Mutheffer, E’atelaf A., Oreffo, Richard O. C., Zannettino, Andrew, Scammell, Brigitte E., White, Lisa J., El Haj, Alicia J.

Journal:

npj Regenerative Medicine

Year:

2018

Language:

english

File:

PDF, 3.39 MB

english, 2018

14

Combinatorial Delivery of Bioactive Molecules by a Nanoparticle-Decorated and Functionalized Biodegradable Scaffold

Czekanska, Ewa, Geng, Jin, Glinka, Michael, White, Kate, Kanczler, Janos M., Evans, Nicholas D, Oreffo, Richard O, Bradley, Mark

Journal:

Journal of Materials Chemistry B

Year:

2018

Language:

english

File:

PDF, 1.30 MB

english, 2018

15

Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model

Vishnubalaji, Radhakrishnan, Atteya, Muhammad, Al-Nbaheen, May, Oreffo, Richard O. C., Aldahmash, Abdullah, Alajez, Nehad M.

Journal:

Stem Cells International

Year:

2015

Language:

english

File:

PDF, 17.39 MB

english, 2015

16

Cell Engineering and Regeneration || Cell Culture Conditions: Cultivation of Stem Cells Under Dynamic Conditions

Gimble, Jeffrey M., Marolt, Darja, Oreffo, Richard, Redl, Heinz, Wolbank, Susanne

Year:

2018

Language:

english

File:

PDF, 609 KB

english, 2018

17

A blueprint for translational regenerative medicine

Armstrong, James P. K., Keane, Timothy J., Roques, Anne C., Patrick, P. Stephen, Mooney, Claire M., Kuan, Wei-Li, Pisupati, Venkat, Oreffo, Richard O. C., Stuckey, Daniel J., Watt, Fiona M., Forbes, S

Journal:

Science Translational Medicine

Year:

2020

File:

PDF, 385 KB

2020

18

Effects of interferon alpha on human osteoprogenitor cell growth and differentiation in vitro

Richard O.C. Oreffo, Silke Romberg, Amarjit S. Virdi, Clive J. Joyner, Sigurd Berven, James T. Triffitt

Journal:

Journal of Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 532 KB

english, 1999

19

Human bone marrow osteoprogenitors express estrogen receptor-alpha and bone morphogenetic proteins 2 and 4 mRNA during osteoblastic differentiation

Richard O.C. Oreffo, Vesna Kusec, Silke Romberg, James T. Triffitt

Journal:

Journal of Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 258 KB

english, 1999

20

Mutational specificity: Mutational spectra of tamoxifen-induced mutations in the livers of lacl transgenic rats

Reginald Davies, Victor I. C. Oreffo, Stuart Bayliss, Phuong-Anh Dinh, Kathryn S. Lilley, Ian N. H. White, Lewis L. Smith, Jerry A. Styles

Journal:

Environmental and Molecular Mutagenesis

Year:

1996

Language:

english

File:

PDF, 320 KB

english, 1996

21

Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia

Victor I. C. Oreffo, Susan Robinson, Ming You, Mau-Ching Wu, Alvin M. Malkinson

Journal:

Molecular Carcinogenesis

Year:

1998

Language:

english

File:

PDF, 400 KB

english, 1998

22

Retroviral marking of human bone marrow fibroblasts: In vitro expansion and localization in calvarial sites after subcutaneous transplantation in vivo

Richard O.C. Oreffo, Amarjit S. Virdi, James T. Triffitt

Journal:

Journal of Cellular Physiology

Year:

2001

Language:

english

File:

PDF, 435 KB

english, 2001

23

Biomineralized Polysaccharide Capsules for Encapsulation, Organization, and Delivery of Human Cell Types and Growth Factors

D. W. Green, I. Leveque, D. Walsh, D. Howard, X. Yang, K. Partridge, S. Mann, R. O. C. Oreffo

Journal:

Advanced Functional Materials

Year:

2005

Language:

english

File:

PDF, 643 KB

english, 2005

24

Cover Picture: Biomineralized Polysaccharide Capsules for Encapsulation, Organization, and Delivery of Human Cell Types and Growth Factors (Adv. Funct. Mater. 6/2005)

D. W. Green, I. Leveque, D. Walsh, D. Howard, X. Yang, K. Partridge, S. Mann, R. O. C. Oreffo

Journal:

Advanced Functional Materials

Year:

2005

File:

PDF, 9.43 MB

2005

25

Porous Polymer and Cell Composites That Self-Assemble In Situ

A.K. Salem, F.R.A.J. Rose, R.O.C. Oreffo, X. Yang, M.C. Davies, J.R. Mitchell, C.J. Roberts, S. Stolnik-Trenkic, S.J.B. Tendler, P.M. Williams, K.M. Shakesheff

Journal:

Advanced Materials

Year:

2003

Language:

english

File:

PDF, 432 KB

english, 2003

26

Coating of Human Mesenchymal Cells in 3D Culture with Bioinorganic Nanoparticles Promotes Osteoblastic Differentiation and Gene Transfection

R. Gonzalez-McQuire, D. W Green, K. A Partridge, R. O. C. Oreffo, S. Mann, S. A. Davis

Journal:

Advanced Materials

Year:

2007

Language:

english

File:

PDF, 566 KB

english, 2007

27

Bone-like Resorbable Silk-based Scaffolds for Load-bearing Osteoregenerative Applications

Andrew M. Collins, Nick J. V. Skaer, Tom Gheysens, David Knight, Caroline Bertram, Helmtrud I. Roach, Richard O. C. Oreffo, Sonja Von-Aulock, Teodora Baris, John Skinner, Stephen Mann

Journal:

Advanced Materials

Year:

2009

Language:

english

File:

PDF, 425 KB

english, 2009

28

Clay Gels For the Delivery of Regenerative Microenvironments

Jonathan I. Dawson, Janos M. Kanczler, Xuebin B. Yang, George S. Attard, Richard O.C. Oreffo

Journal:

Advanced Materials

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

29

Clay Hydrogels: Clay Gels For the Delivery of Regenerative Microenvironments (Adv. Mater. 29/2011)

Jonathan I. Dawson, Janos M. Kanczler, Xuebin B. Yang, George S. Attard, Richard O.C. Oreffo

Journal:

Advanced Materials

Year:

2011

File:

PDF, 4.08 MB

2011

30

Versatile Biocompatible Polymer Hydrogels: Scaffolds for Cell Growth

Ferdous Khan, Rahul S. Tare, Richard. O. C. Oreffo, Mark Bradley

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 849 KB

english, 2009

31

Versatile Biocompatible Polymer Hydrogels: Scaffolds for Cell Growth

Ferdous Khan, Rahul S. Tare, Richard. O. C. Oreffo, Mark Bradley

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 850 KB

english, 2009

32

Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions

Helmtrud I. Roach, Norikazu Yamada, Kelvin S. C. Cheung, Simon Tilley, Nicholas M. P. Clarke, Richard O. C. Oreffo, Shoichi Kokubun, Felix Bronner

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

33

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

Ko Hashimoto, Richard O. C. Oreffo, Marc B. Gibson, Mary B. Goldring, Helmtrud I. Roach

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 553 KB

english, 2009

34

Development of a slow non-viral DNA release system from PDLLA scaffolds fabricated using a supercritical CO2 technique

Mieke Heyde, Kris A. Partridge, Steven M. Howdle, Richard O.C. Oreffo, Martin C. Garnett, Kevin M. Shakesheff

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 530 KB

english, 2007

35

The interaction of human bone marrow cells with nanotopographical features in three dimensional constructs

C.C. Berry, M.J. Dalby, R.O.C. Oreffo, D. McCloy, S. Affrosman

Journal:

Journal of Biomedical Materials Research Part A

Year:

2006

Language:

english

File:

PDF, 1.00 MB

english, 2006

36

Interactions with nanoscale topography: Adhesion quantification and signal transduction in cells of osteogenic and multipotent lineage

Manus J. P. Biggs, R. Geoff Richards, Nikolaj Gadegaard, Rebecca J. McMurray, Stanley Affrossman, Chris D. W. Wilkinson, Richard O. C. Oreffo, Mathew J. Dalby

Journal:

Journal of Biomedical Materials Research Part A

Year:

2009

Language:

english

File:

PDF, 816 KB

english, 2009

37

Tissue-Specific Stem Cell Differentiation in an in vitro Airway Model

Zoë Prytherch, Claire Job, Hilary Marshall, Victor Oreffo, Martyn Foster, Kelly BéruBé

Journal:

Macromolecular Bioscience

Year:

2011

Language:

english

File:

PDF, 892 KB

english, 2011

38

Mutational analysis of a dominant oncogene (c-Ki-ras-2) and a tumor suppressor gene (p53) in hamster lung tumorigenesis

Victor I. C. Oreffo, Hsiu-Wei Lin, Paul H. Gumerlock, Susan A. Kraegel, Hanspeter Witschi

Journal:

Molecular Carcinogenesis

Year:

1992

Language:

english

File:

PDF, 371 KB

english, 1992

39

EFFECTS OF BETA MERCAPTOETHANOL ON THE PROLIFERATION AND DIFFERENTIATION OF HUMAN OSTEOPROGENITOR CELLS

KENTARO INUI, RICHARD O.C OREFFO, JAMES T TRIFFITT

Journal:

Cell Biology International

Year:

1997

Language:

english

File:

PDF, 202 KB

english, 1997

40

MODULATION OF OSTEOGENIC DIFFERENTIATION IN HUMAN SKELETAL CELLSIN VITROBY 5-AZACYTIDINE

RACHEL M LOCKLIN, RICHARD O.C OREFFO, JAMES T TRIFFITT

Journal:

Cell Biology International

Year:

1998

Language:

english

File:

PDF, 332 KB

english, 1998

41

Effects of TGFβ and BFGF on the differentiation of human bone marrow stromal fibroblasts

Rachel M Locklin, Richard O.C Oreffo, James T Triffitt

Journal:

Cell Biology International

Year:

1999

Language:

english

File:

PDF, 1.55 MB

english, 1999

42

Acute effects of the Bowman-Birk protease inhibitor in mice

Victor I.C. Oreffo, Paul C. Billings, Ann R. Kennedy, Hanspeter Witschi

Journal:

Year:

1991

Language:

english

File:

PDF, 637 KB

english, 1991

43

The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting

Benjamin J.R.F. Bolland, Janos M. Kanczler, Patrick J. Ginty, Steve M. Howdle, Kevin M. Shakesheff, Douglas G. Dunlop, Richard O.C. Oreffo

Journal:

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

44

Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling

Fahsai Kantawong, Karl E.V. Burgess, Kamburapola Jayawardena, Andrew Hart, Richard J. Burchmore, Nikolaj Gadegaard, Richard O.C. Oreffo, Matthew J. Dalby

Journal:

Year:

2009

Language:

english

File:

PDF, 897 KB

english, 2009

45

Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells

Fahsai Kantawong, Karl E.V. Burgess, Kamburapola Jayawardena, Andrew Hart, Mathis O. Riehle, Richard O. Oreffo, Matthew J. Dalby, Richard Burchmore

Journal:

Acta Biomaterialia

Year:

2010

Language:

english

File:

PDF, 1.26 MB

english, 2010

46

Fabrication of hydroxyapatite sponges by dextran sulphate/amino acid templating

Rosanna Gonzalez-McQuire, David Green, Dominic Walsh, Simon Hall, Jean-Yves Chane-Ching, Richard O.C. Oreffo, Stephen Mann

Journal:

Year:

2005

Language:

english

File:

PDF, 435 KB

english, 2005

47

Osteoprogenitor response to defined topographies with nanoscale depths

Matthew John Dalby, David McCloy, Mary Robertson, Chris D.W. Wilkinson, Richard O.C. Oreffo

Journal:

Year:

2006

Language:

english

File:

PDF, 910 KB

english, 2006

48

The effect of anisotropic architecture on cell and tissue infiltration into tissue engineering scaffolds

M.M.C.G. Silva, L.A. Cyster, J.J.A. Barry, X.B. Yang, R.O.C. Oreffo, D.M. Grant, C.A. Scotchford, S.M. Howdle, K.M. Shakesheff, F.R.A.J. Rose

Journal:

Year:

2006

Language:

english

File:

PDF, 617 KB

english, 2006

49

Computational modelling of cell spreading and tissue regeneration in porous scaffolds

Bram G. Sengers, Mark Taylor, Colin P. Please, Richard O.C. Oreffo

Journal:

Year:

2007

Language:

english

File:

PDF, 571 KB

english, 2007

50

An ex vivo model for chondrogenesis and osteogenesis

Jodie C. Pound, David W. Green, Helmtrud I. Roach, Stephen Mann, Richard O.C. Oreffo

Journal:

Year:

2007

Language:

english

File:

PDF, 2.25 MB

english, 2007